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Its benefits are largely tied to its high binding affinity for androgen receptors (AR) and selective tissue targeting
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van Eijk et al., 2022)
As expected, according to a linear meta-regression model, tirzepatide might decrease AHI in patients with OSA and obesity 102
According to studies, the reduced incretin effect in patients with T2DM may be due to a decrease in the response of -cell to GIP and/or GLP-1 or a decrease in GLP secretion [15, 18, 27, 28]
