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Deficiency of complex II of the mitochondrial respiratory chain in late-onset optic atrophy and ataxia

The progression of HFL-I cells from the G1 to the S phase was blocked, resulting in a build-up of cells in the G1 phase (which were unable to enter the S phase), a relative increase in the number of cells in the G2/M phase, a decrease in the expression of Bcl-2 and survivin mRNA, an increase in the expression of Bax mRNA, and an increase in the number of apoptotic cells (Zhang, 2010)

There are various factors that play a role in causing these injuries

The effects and mechanisms of acupuncture for post-stroke cognitive impairment: Progress and prospects

According to the authors, LRIF1 mutations are a rare reason for FSHD and should thus only be considered in FSHD2 when tested negative for SMCHD1 mutations [47]