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We also summarize potential therapeutic drugs related to glucose metabolism based on results from current cellular and animal model studies

The first step of glutathione synthesis involves the formation of glutamylcysteine from glutamate and cysteine in an ATP dependent reaction catalysed by glutamate-cysteine-ligase (GCL) which requires either Mg 2+ or Mn 2+ as a cofactor

In terms of prognosis, the 5-year event-free survival (EFS) was 84.9% (SE 3.4%) for pegaspargase and 88.1% (SE 3.0%) for calaspargase pegol

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3.7 In vivo antitumor efficiency Based on the collaborative eradication of cancer cells in a laboratory setting and the specific accumulation of tumors in living organisms, we proceeded to investigate the anti-cancer characteristics of CDCZA nanoparticles in mice with Eca-109 tumors