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According to the Centers for Disease Control (CDC), roughly 2% of the population, or about 6.5 million people, suffer from B-12 deficiency

Results can vary depending on individual factors and consistency of use

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Up to 40% of patients with metastatic TNBC will develop brain metastasis or leptomeningeal disease
To control for interindividual variabilities due to heart rate, blood flow or rate of contrast injection, each voxels leakage rate was normalized to that of the superior sagittal sinus

For instance, mice with genetic deletion in glutamate transporter-1 exhibit reduced glutamate clearance, and consequently display abnormal cell death in motor neurons, reminiscent of amyotrophic lateral sclerosis (Staats and Van Den Bosch, 2009)