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Thus, there are several unanswered questions that need to be studied with extensive preclinical mechanistic studies to explore the specific roles of antioxidants with respect to types, forms and stages of brain tumors in order to achieve their clinical utility in brain cancer management

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[DOI] [PubMed] [Google Scholar] Kujawinski E

6466 Though most of the ECS research indicates that the itch response is primarily modulated through CB1 receptors in the CNS, 6769 some reports argue the involvement of peripheral CB1 receptors could also be a potent contributor to itch

These impairments can significantly impact a persons ability to perform basic tasks and maintain independence