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The authors also acknowledge Hui-Ying Wang of the Public Platform of State Key Laboratory of State Key Laboratory of Natural Medicines at China Pharmaceutical University for the use of analytical instrumentation facilities

These effects are linked to alterations in mitochondrial structure, such as changes in membrane phospholipid composition, viscosity, and the structure and function of lipid microdomains, which in turn affect membrane-bound signaling proteins (65, 66)

Redox shuttles in the brain

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For example, chronic alcohol misuse can lead to the accumulation of fluids and solutes (e.g., electrolytes), which increase overall body fluid volume

Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice