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These include Ginkgo biloba, Rhodiola rosea, Panax ginseng, Schisandra chinensis, and Cordyceps sinensis, each of which has demonstrated capacity to upregulate VEGF expression under hypoxic or inflammatory stress while also exerting antioxidant, mitochondrial-supportive, and endothelial-protective effects

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Hypothalamic-pituitary-adrenal (HPA) axis and cortisol dysregulation The dysregulation of the HPA axis is a significant pathway linking depression with T2DM [70]

Epithalon is a synthetic peptide made of just four amino acids (Alanine-Glutamic-Aspartic-Glycine)

The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores

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