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[DOI] [PubMed] [Google Scholar] Shimomura N., Honma M., Chiba S., Tahara S., Mizutani J

It is known for its powerful detoxifying properties and ability to combat oxidative stress

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Furthermore, elevated pro-inflammatory mediators such as TNF, IL, IL6, iNOS, and COX two have been found in the striatum and substantia nigra, according to this study (Tansey et al., 2007)

The association observed with GPX3 could similarly reflect changes in oxidative stress, where the decrease in GPX3 is in parallel with gains in endogenous insulin secretion and improved glycaemic control

Specifically, an ACYP2 variant was associated with ototoxicity in both children and adults, and TPMT variants were associated with ototoxicity in children