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FOXO4-DRI research dosage protocols typically involve reconstituting lyophilised peptide at 1mg per 1mL bacteriostatic water, administered subcutaneously at 510mg per kilogram body weight in murine models, with observation windows extending 7296 hours post-administration to assess senescent cell clearance through SA--gal staining and p16INK4a marker expression

This effect was efficiently reverted by IGF-1 administration [161]