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As demonstrated by Shimizu et al., dimethyl fumarate, an Nrf2 agonist, exhibited the capacity to protect ARPE 19 cells and mouse retinas from blue light-induced ferroptosis-like injury in AMD, a consequence of promoting Nrf2 nuclear translocation (140)

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While hematocrit values are the major determinant of blood viscosity, as a more packed fluid (increased hematocrit) blood is more resistant to flow (increased viscosity), a loss of deformability in RBCs may increase viscosity significantly (34) due to increased end-over-end tumbling (61)

Produced by the hypothalamus, GHRH signals the pituitary glands somatotrophs to release GH

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