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& Yan, C

Creagan et al

& Mango, S

Longhitano L, Distefano A, Musso N et al (2024) (+)-Lipoic acid reduces mitochondrial unfolded protein response and attenuates oxidative stress and aging in an in vitro model of non-alcoholic fatty liver disease

[93] reported that RNAi mediated silencing of OcSSI2 , which impacts fatty acid desaturase activity by increasing and decreasing the level of stearic acid and oleic acid, and exhibited strengthen resistance to bacteria ( Xanthomonas oryzae pv.oryzae) and blast fungus Magnaporthe grisea in rice

The direct intranasal drug delivery approach to therapeutics holds great promise for the treatment of central nervous system (CNS) disorders, as this route is non-invasive, bypasses the BBB, enhances the bioavailability, facilitates drug dose reduction, and reduces adverse systemic effects