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Ongoing research is focused on increasing their targeting specificity and transfection efficiency [127,128,129,130,131,132]

Among these agents, melatonin has received the most attention as a ferroptosis inhibitor in IR-induced tissue injuries
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Cibinetide (ARA-290) offers a more balanced, preventative modulation via the innate repair receptor, potentially better suited for long-term use in active individuals, with added benefits for neuropathic pain including sciatica through nerve-ending inflammation reduction
doi: 10.1002/ijc.25060 267 BauwensEPareTMeurantSBouriezIHannartCWraACet al

Maternal Spirulina supplementation during pregnancy and lactation partially prevents oxidative stress, glial activation and neuronal damage in protein malnourished F1 progeny