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At organism-interface sites, extracellular and membrane-proximal ROS shape host defense and vascular tone: in professional phagocytes, NOX2 assembles at the phagosomal membrane to generate large bursts of O 2 into the lumen, where rapid dismutation and the action of myeloperoxidase convert upstream oxidants into hypochlorous acid (HOCl), a potent microbicidal species that collaborates with proteases and pH control to sterilize engulfed targets (Nauseef 2019)

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Propionibacterium acnes-associated neurosarcoidosis: a case report with review of the literature

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Trace elements, such as zinc (Zn), copper (Cu), magnesium (Mg), and iron (Fe), play pivotal roles in maintaining cellular homeostasis and enzymatic function, particularly in antioxidant defense systems 15

Vitamin D is also a critical nutrient because adequate levels are essential for normal immune system communication
