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High levels of other biogenic amines can reduce the ability of DAO to break down histamine.[ref] DAO degrades histamine into imidazole acetaldehyde, which is then quickly oxidized into imidazole acetic acid.[ref] Histamine + [DAO enzyme] Imidazole acetaldehyde + NH3+H2O2 HMNT enzyme inactivates the histamine produced in your cells In addition to its role in allergic response and in the gut, histamine is produced and functions as a neurotransmitter within the brain and nervous system

Glutathione plays a central role in neutralizing free radicalsunstable molecules that can cause oxidative stress and damage cells

Turner PC, Snyder JA (2021) Development and limitations of exposure biomarkers to dietary contaminants mycotoxins

Insights into the structure and function of the hippocampus: implications for the pathophysiology and treatment of autism spectrum disorder

Disease states Studies have shown that plasma Hcy level is elevated in some disease states, such as various cancers (40), psoriasis (41), hypothyroidism (42), diabetes (43), and renal dysfunction (44), and the specific mechanism remains to be further studied

Focus areas may include: Hormone Balance - Low testosterone, perimenopause & menopause Gut Health - digestion, microbiome, and GI issues Inflammation & Immunity - autoimmune conditions and chronic inflammation Detoxification & Environmental Toxins -allergies, sensitivities, and heavy metals Cardiometabolic Health -heart health, blood sugar and cholesterol Nutrition & Lifestyle - metabolism, energy, and weight management Chronic Disease Identification - thyroid function and cancer screenings Your personalized plan may include medical grade purity tested supplements from Fullscript , evidence-based nutritional strategies from That Clean Life