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OCA also mitigates liver fibrosis (84, 129), though clinical use faces challenges from side effects like pruritus (130, 131)

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[DOI] [PMC free article] [PubMed] [Google Scholar] [252].Spitzer S, Volbracht K, Lundgaard I, Kradttir RT, Glutamate signalling: A multifaceted modulator of oligodendrocyte lineage cells in health and disease, Neuropharmacology 110(Pt B) (2016) 574585