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The enhanced lipophilicity conferred by acetylation relative to standard L-carnitine facilitates more efficient blood-brain barrier penetration in research subjects, contributing to the neurological research interest documented for ALCAR specifically

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Notably TMAO concentrations have also been linked to hypertension, a major risk factors for aortopathy [67]

A last observation carried forward method was prospectively defined and used for missing data if the subjects had data at least for the first two visits

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