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RBCs normally contain a high concentration of bioavailable or free heme, as shown by dialysis experiments [230], derived by the auto-oxidation of 300 million molecules of hemoglobin in each RBC

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doi:10.1002/(SICI)1098-1136(199709)21:1 3.0.CO;2-W Hassel B, Westergaard N, Schousboe A, Fonnum F (1995) Metabolic differences between primary cultures of astrocytes and neurons from cerebellum and cerebral cortex