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2013: Description of a new species and record of Bactrocera Macquart (Diptera,Tephritidae) from China
2014;2014 doi: 10.1136/bcr-2013-201567

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Several TCA cycle intermediates, including succinate, fumarate, and 2-oxoglutarate (-ketoglutarate) can function as potent regulators of gene expression
Applying the above, if an athlete takes one dose of 100 micrograms and another dose of 100 micrograms 8 hours later, they reached the maximum allowed for that 24-hour period

Effects of altered pyruvate dehydrogenase activity on contracting skeletal muscle bioenergetics