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Numerous studies have evidenced that oxidative stress modifies various functional responses of vascular endothelial cells and is considered to play a critical role in developing CVDs such as hypertension, atherosclerosis, myocardial infarction, heart failure, and so on

[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Fagerberg L., Hallstrm B.M., Oksvold P., Kampf C., Djureinovic D., Odeberg J., Habuka M., Tahmasebpoor S., Danielsson A., Edlund K., et al
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MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis

Evidence of neuroinflammation includes activated microglia and astrocytes found in post-mortem brain tissue (Pardo et al

Neurology 52 , 473478 (1999)