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Lewy bodies and -synuclein accumulation in the SN are hallmarks of the neuropathology of PD

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As a nutrient sensor, mTOR has important homeostatic functions to regulate energy metabolism and support neuronal growth and plasticity

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This study aims to investigate the molecular mechanism by which sulfurized garlic (SAC) inhibits ferroptosis through targeting Keap1/Nrf2/GPX4 signaling pathway, thereby restoring intestinal epithelial cell barrier function and alleviating ulcerative colitis (UC)

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