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Description
Susceptibility loci largely overlap with the loci detected in other complex immune diseases affecting different organs: PSC and PBC shared common risk loci with multiple sclerosis, celiac disease, inflammatory bowel disease (IBD), rheumatoid arthritis and type 1 diabetes (Mells et al., 2013)

EBioMedicine 11 , 296301 (2016)

Pereira-Castro I, Moreira A

Pharmacological profiles of opioid ligands at kappa opioid receptors

Beyond this, a range of other miRNAsincluding miR-199a-5p, miR-214-3p, miR-153-3p, miR-129-5p, miR-21, miR-30a, miR-145, miR-30b, miR-200, miR-302c, miR-34a, and miR-29bhave been reported to interact with hypoxia-inducible factor-1 (HIF-1), a key regulator in fibrotic signaling (Sandoval et al., 2016

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