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However, overexpression of PGC-1 reduces autophagy marker levels, improves mitochondrial metabolic function and antioxidant capacity, thereby alleviating muscle atrophy, offering a potential approach to age-related sarcopenia (80)

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Although NAC co-exposure was not able to compensate for THC-induced GABA reductions, it normalized relative DA content, spontaneous EPSCs frequency, gamma power and behavioural abnormalities, underscoring the relevance of excitation/inhibition balance and its sensitivity to oxidative stress in these phenomena

In the oxidized state, PDI acts as a disulfide donor

But with age, chronic stress, poor nutrition, and environmental toxin exposure, your body's natural glutathione levels decline faster than they can be replenished

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