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In biochemical and cellular research, GHK-Cu is widely studied for its role in peptidemetal interactions, extracellular matrix signaling, copper-dependent molecular regulation, and cellular communication pathways

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In the D-Gal + FOXO4-DRI group, mice also received D-galactose injections and, after 4 weeks, were given intraperitoneal injections of FOXO4-DRI (5 mg/kg, MCE, HY-P4157) every 2 days for 4 weeks, followed by tissue collection