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882-P: Eloralintide, a selective, long-acting amylin receptor agonist for obesityphase 1 proof of concept

Safety Considerations Injectable human data are limited, with possible injection-site reactions, hypersensitivity, and copper-related considerations

In vitro enzyme-inhibition characterization

Zhou T, Xie Y, Hou X, Bai W, Li X, Liu Z, et al

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pH Compatibility Analysis Reveals a Shared Stability Window Comparing the optimal pH ranges for each peptide and the reconstitution vehicle: Copper tripeptide (GHK-Cu): 5.07.0 (optimal 5.57.0) Thymosin fragment (TB-500): 4.57.5 (optimal 6.07.5) Body protection compound (BPC-157): 6.58.5 (stable across wider range, including more acidic conditions) Bacteriostatic water: pH 5.7 (range 4.57.0) The overlapping stability region spans approximately pH 5.57.0 , with the bacteriostatic waters pH of 5.7 falling near the optimal range for the copper tripeptide and within acceptable ranges for all three peptides