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Blood samples were collected before the initiation of treatment and at the end of the study period to isolate polymorphonuclear neutrophils and monocytes

SFN occurs when the tiny, unmyelinated peripheral nerves that control pain sensation and autonomic blood vessel constriction become damaged by oxidative stress and autoimmune cross-reactivity

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When we planned and designed the study no persuasive data for clinical endpoints existed and we had to base the initial power calculations on inflammatory markers in humans under L-Carnitine treatment

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Because of this, many people turn to supplements like L-Carnitine to boost energy or L-Theanine to maintain a sense of calm