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Constipation Tirzepatide slows gastric motility, which frequently causes constipation
[15] Serious but infrequent events-such as angioedema, bronchospasm, hypotension, or urticaria-reflect IgE-mediated hypersensitivity and may require desensitization or substitution with hydroxocobalamin

2020 Jan 6;11(1):15

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