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The transduction process and establishment of stable cell lines were performed according to the manufacturers instructions

Brain glutathione concentrations were measured using 7T magnetic resonance spectroscopy, and GSH/GSSG redox ratios were measured from blood samples

The pathogenesis of CI/RI involves multiple aspects, including excessive ROS-induced neuronal oxidative stress [91], inflammation [92], and cell apoptosis [93]

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During the conversion of serine to glycine, an additional carbon unit is provided for onecarbon metabolism

These findings are supported by the well-known relationship between metabolic health and brain health