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10.1126/science.1151526 175 YuD.ZhaoY.WangH.KongD.JinW.HuY.et al (2021)

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Myeloid-Derived Suppressor Cells as Regulators of the Immune System

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2.2 Epigenetic Modifications Regulate Drug Targets and Bypass Signaling Pathways Over the past decade, targeted agents have been steadily introduced into clinical trials for treating recurrent OC, namely, the anti-VEGFR agent bevacizumab, PARP inhibitors (olaparib, niraparib, and rucaparib), the anti-MEK inhibitor trametinib, and anti-HER2 pertuzumab

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