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Flavonols , a subgroup of flavonoids, are polyphenolic natural compounds recognized for their strong antioxidant properties, largely attributed to their hydroxyl substitution patterns

Individual variation in MC4R sensitivity exists

Interestingly, some evidence also points to microglial contexts, where AX has been shown to suppress the production of inflammatory mediators in LPS-stimulated BV-2 microglial cells, suggesting potential neuroprotective effects [55]

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