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Upon binding of the death ligand, the death domain of the intracellular region of the receptor recruits Fas-associated death domain protein (FADD) via the adaptor protein TNFRSF1A-associated death domain, forming the death-inducing signaling complex (68)

10.1152/physrev.00005.2017 109 Silwal-PanditL.LangerdA.Brresen-DaleA.-L

Mendelian susceptibility to mycobacterial disease is a group of primary immunodeficiencies characterized by severe infections with weakly virulent intracellular pathogens