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Circulating iron uptake in the form of two ferric iron (Fe 3+ ) bound to transferrin (TF) is achieved by binding to transferrin receptor protein 1 (TFR1) and subsequently triggering endocytosis [70]

The gut-brain axis, the bidirectional communication between intestinal and central nervous systems, may contribute to symptom generation
But despite the ease of accessing them today, and gushing reviews online from many well-respected longevity thought leaders, many skeptics flag major safety and efficacy issues

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Goodarzi MO, Dumesic DA, Chazenbalk G, Azziz R
