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Shapiro, T

The fate of chemically reactive XSH fragments is discussed in Reactive Sulfur-Containing Fragments Generated by -Lyase Reactions Involving Halogenated Alkene Cysteine S-Conjugates section. 10.17.6.4

doi: 10.1002/jimd.12011, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 59

A BLAST E-value of 1 10 220 was employed

Studies have shown that FDX1 is upregulated in platinum-resistant ovarian cancer cell lines (A2780/DDP and SKOV3/DDP), inhibiting ferroptosis and resulting in cisplatin resistance

Finally, it is proposed that a network of interacting epigenetic mechanisms, including protein synthesis inhibition, oxidative stress and the activation of specific cell signalling pathways is responsible for OTA carcinogenicity [86] (Fig.7) Trichothecenes Trichothecenes (TCs) are mycotoxins produced mostly by members of the genus and other genera (e.g