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Wang X, Zhao H, Yan W, Liu Y, Yin T, Wang S, et al

These mice had a reductive stress phenotype [46, 47], characterized, in part, by an increased activity of GPx1 and catalase as well as increased GSH/GSSG and a corresponding increased expression of enzymes involved in glutathione biosynthesis and GSSG recycling to GSH

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Ervin, E

10.1016/j.biopha.2003.11.004 28 EyoU

2 Specifically, the authors found that treating cells with the Cu ionophore elesclomol at concentrations as low as 40 nM increased intracellular Cu levels and triggered cuproptosis