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doi: 10.1152/ajprenal.00375.2015, 86

Glucose-6-phosphate dehydrogenase (G6PD) deficiency: High doses of vitamin C in CB 12 injection could cause hemolysis, a condition where red blood cells are destroyed prematurely, in patients with G6PD deficiency

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These include TRPC channels (e.g., TRPC6 in humans ( 2+ influx and membrane vesiculation ( 2+ activates Ca 2+ -sensitive Gardos channels (KCa3.1, encoded by KCNN4), resulting in K + efflux, membrane hyperpolarization, Cl loss, and subsequent osmotic cell shrinkage (Rapetti-Mauss et al., 2017)

12 patches (18mm)

Furthermore, PI staining showed that with MT treatment, MP-induced cell death was rescued in a concentration-dependent manner (Fig