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Front Pharmacol:11

The study included all patients with any type of melasma

45 BCAA has an important role in tumor and metabolic diseases as an essential amino acid

170,171,172,173 However, compared with antibodies, aptamers have several advantages, including high thermal and physiological stability, low immunogenicity, and a wider range of target specificity

In addition, W-box mutants also show comparable affinities for both epsins

Subsequently, ribosomal protein S6 (RPS6), the subunit of eukaryotic translation initiation factor 2 (eIF2), and eukaryotic translation elongation factor 2 (eEF2) undergo phosphorylation (Dong et al., 2018)