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To take the promise of something like leucovorin seriously, you need rigorous, double-blind, placebo-controlled, transparent trials, says Lerner

One of the major constraints is the delivery of these drugs, which significantly limits their clinical application

Availability of data and materials The datasets used and/or analysed during the current study are available from the corresponding authors on reasonable request

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Current research suggests it may serve as a versatile tool for studying cytoskeletal regulation, cellular migration, and tissue response processes in controlled experimental environments