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The best known function of the CYP enzymes is the detoxification of compounds, such as anti-cancer drugs and xenobiotics in the liver

Eur J Pharmacol 861:172593 Luetic K, Sucic M, Vlainic J, Halle ZB, Strinic D, Vidovic T et al (2017) Cyclophosphamide induced stomach and duodenal lesions as a NO-system disturbance in rats: L-NAME, L-arginine, stable gastric pentadecapeptide BPC 157

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While tiny, long-term doses of aflatoxin have immunologic or nutritional effects, large doses cause direct death and injury Marroqun-Cardona et al

GI-related events may occur under rapid introduction or elevated dosing, typically mitigated through controlled administration protocols