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Another study also explored the potential role of Humanin in influencing insulin sensitivity
As shown in Figure 7A, the rate of uptake in these transfectant cells increased more than twice, and this increased uptake was inhibitable by excess glutamate (data not shown)
Tumor heterogeneity further complicates this landscape, as the extent of GSH dependency varies across tumor types, metabolic states, and microenvironments, with poorly defined consequences for therapeutic response
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