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Blood 100, 42014208

Apr 27 2023;28(9)doi:10.3390/molecules28093771 Liu B, Kou J, Li F, et al

Novel 3,4-dihydroquinolin-2(1H)-one derivatives as dual inhibitor targeting AKR1B1/ROS for treatment of diabetic complications: Design, synthesis, and biological evaluation

Autophagy inhibition was observed to enhance the production of ROS-associated macrophage migration inhibitory factor (MIF), which induced and continuously promoted M1 macrophage polarization (98)

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