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[DOI] [PubMed] [Google Scholar] 67.Kunst C., Schmid S., Michalski M., Tmen D., Buttenschn J., Mller M., Glow K
PMID: 33309287
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Long-term studies using obese animal models have looked into how this fragment affects body weight and metabolic markers over longer treatment windows
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By altering TXNIP expression, increasing SIRT2 activity, and decreasing mitochondrial ROS and dysfunction, silymarin prevents the activation of the NLRP3 inflammasome
