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Wnt4 signaling is known to play a key role in nephrogenesis, as its activation promotes renal fibrosis in mouse models (Kispert et al., 1998
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[DOI] [PMC free article] [PubMed] [Google Scholar] 5.erman AA, Solak SS, Altunay , Kknal NA

Its central function involves the reduction of complex hydroperoxides into their respective alcohols often using reduced Glutathione (GSH) as a reducing agent
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