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Data are stored in secure servers in the field office and in a data management centre (DMC) in Kathmandu

Metabolic pathway requiring 5-deoxyadenosylcobalamin The figure illustrates the metabolic pathway for the vitamin B 12 -dependent enzyme L-methylmalonyl-CoA mutase, which converts L-methylmalonyl-CoA into succinyl-CoA for entry into the citric acid cycle

Data are mean SD

High dose vitamin C infusions given intravenously (directly into the bloodstream) can reach much higher levels than when taken orally

Sharps disposal: Sharps containers are typically provided on NHS prescription or through local authority schemes

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