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Description
5-HT is an important monoamine neurotransmitter in the central nervous system, and a decrease in its levels in the synaptic gap attenuates the activation of postsynaptic membrane 5-HT receptors (27), which destabilizes the neural loop of mood regulation and leads to psychiatric symptoms such as anxiety (26)

However, maintaining consistent levels in the body may support long-term effectiveness

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PMID 15384578
