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Reduction of Inflammation Inflammation is a common response after surgery, often contributing to pain and delayed healing

The peptide modulates NO production in ways that support blood flow, reduce inflammation, and protect tissues from oxidative damage

Patients receive training on proper injection technique during their first appointment

These are most common during initial dose

The mechanistic rationale is strong, the safety profile is established, and the observation that psoriatic arthritis patients have lower thymosin alpha-1 levels is suggestive

The authors sincerely thank Professor Graham Rook (University College London, United Kingdom) for discussions on his Old Friends Hypothesis and critical reading of the manuscript, and Professor Hanna Kmita (Adam Mickiewicz University, Poznan, Poland) for a critical reading of the manuscript and helpful suggestions for its improvement