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Identification of shared oxidative stress related hub genes in Nafld and atherosclerosis using bioinformatics and machine learning

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Li and Zhou, 2017), leading to hepatocellular injury and fibrosis (Kitano et al., 2022)

Indeed, melatonin is highly permeable to cell membranes and easily crosses the bloodbrain barrier 51 , ensuring a good therapeutic profile for brain diseases, and is also able to accumulate into mitochondria, probably via GLUT/SLC2A and PEPT1/2 carriers 52,53