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[5] Use of Lipo-C Injection is contraindicated in patients with known hypersensitivity to methionine, choline salts, carnitine, dexpanthenol, or any formulation excipients, as well as in individuals with severe hepatic failure in whom augmented methionine intake could precipitate hypermethioninemia and encephalopathy

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The N- acetyl-cysteine thioethers, also known as mercapturic acids, are the excreted metabolites of industrial toxic organic chemicals [36] and this mechanism is considered to play a role in the kidney carcinogenesis by halogenated alkenes

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