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Front Neurol 12:650752 Kim J, Hemachandran S, Cheng AG, Ricci AJ (2022) Identifying targets to prevent aminoglycoside ototoxicity

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The rhythm of the enzyme expression drives the oscillation of NAD + levels, and the synthesis of NAD + is involved in the process of aging and lipid metabolism ( + regulates the circadian clock system through SIRT1