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In addition, KD was associated with reduced expression of inflammatory genes, including COX-2 and ALOX5 (5-lipoxygenase), further supporting a link between ketosis and modulation of immune-related signaling pathways in MS [120, 121]

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An animal study showed bone loss associated with oxidative stress in ovariectomized mice compared to healthy controls [20]

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Loree JM , Dasari A, Shaheed M, Gothwal H, Singh K, Shaheed H, Mangal R, Gothwal S, Willis J, Overman MJ, Kopetz S , Singh Raghav KP

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