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10.1016/j.msard.2022.104048 80 KellorM.FrostJ.SilberbergN.IversenI.CummingsR

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Most participants (81%) reported slowly increasing dosage over 1 month per ANRC guidelines, which were designed to reduce the risk of adverse effects (AE)

It is possible that humans can convert linoleic acid to CLA in their owns guts, as both Lactobacillus and Bifidobacterium bacterial species found in the gut microbiomes of humans have been shown to convert linoleic acid to CLA (Wu et al

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The authors also acknowledge the Gujarat Biotechnology Research Centre (GBRC), Ahmedabad, for providing access to the LC-MS/MS facility and technical support for metabolomic analysis