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A plethora of investigations have illuminated the characteristic alterations of ferroptosis and ferritinophagy, including system Xc-dysfunction, aberrant iron metabolism, and lipid peroxidation, across diverse musculoskeletal conditions such as osteoarthritis, osteosarcoma, and osteoporosis

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doi: 10.1111/imm.13059 129

doi: 10.1159/000356040

Using natural products as tools to define how cellular stress links to inflammatory status may reveal opportunities for selective reprogramming of cellular metabolism to alter immune and inflammatory responses in health and disease

Since products containing synthetic cannabamimetics may not list all their ingredients on the packaging label, the effects of the product could also be different than what the user may expect